ARTERIOSCLEROSIS
\ɑːtˈi͡əɹɪˌɒskləɹˈə͡ʊsɪs], \ɑːtˈiəɹɪˌɒskləɹˈəʊsɪs], \ɑː_t_ˈiə_ɹ_ɪ__ˌɒ_s_k_l_ə_ɹ_ˈəʊ_s_ɪ_s]\
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Thickening and loss of elasticity of arterial walls. Atherosclerosis is the most common form of arteriosclerosis and involves lipid deposition and thickening of the intimal cell layers within arteries. Additional forms of arteriosclerosis involve calcification of the media of muscular arteries (Monkeberg medial calcific sclerosis) and thickening of the walls of small arteries or arterioles due to cell proliferation or hyaline deposition (arteriolosclerosis).
By DataStellar Co., Ltd
By Willam Alexander Newman Dorland
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The hardening and thickening of the intima and, to a lessening degree, of the media and adventia of an artery by an increase of connective and elastic tissue, together, frequently, with a deposit of lime salts, following fatty infiltration of the three coats. [Gr.]
By Smith Ely Jelliffe
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.