C3C
\sˈiː θɹˈiː sˈiː], \sˈiː θɹˈiː sˈiː], \s_ˈiː θ_ɹ_ˈiː s_ˈiː]\
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An inactivated form of COMPLEMENT 3B; (C3b). Complement 3b is inactivated with the help of two regulatory factors, COMPLEMENT FACTOR H and COMPLEMENT FACTOR I. COMPLEMENT FACTOR H; (C3b inactivator accelerator) makes C3b susceptible to the serine protease, COMPLEMENT FACTOR I; (formerly called KAF, C3bINF, or enzyme 3b inactivator), to form iC3b. Then COMPLEMENT FACTOR I and a trypsin-like proteolytic enzyme further cleave iC3b into C3c and C3dg.
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