EXTENUATIVE

\ɛkstˈɛnjuːətˌɪv], \ɛkstˈɛnjuːətˌɪv], \ɛ_k_s_t_ˈɛ_n_j_uː_ə_t_ˌɪ_v]\
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1899 - The american dictionary of the english language.
By Daniel Lyons

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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