L714,465
\ˈɛl sˈɛvənhˈʌndɹədən fˈɔːtiːn θˈa͡ʊzənd fˈɔːhˈʌndɹədən sˈɪkstifˈa͡ɪv], \ˈɛl sˈɛvənhˈʌndɹədən fˈɔːtiːn θˈaʊzənd fˈɔːhˈʌndɹədən sˈɪkstifˈaɪv], \ˈɛ_l s_ˈɛ_v_ə_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n f_ˈɔː_t_iː_n θ_ˈaʊ_z_ə_n_d_ f_ˈɔː_h_ˈʌ_n_d_ɹ_ə_d_ə_n s_ˈɪ_k_s_t_i_f_ˈaɪ_v]\
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A beta-adrenergic antagonist similar in action to PROPRANOLOL. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of migraine and tremor.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.