NEPHRITIC CRISIS

\nɛfɹˈɪtɪk kɹˈa͡ɪsɪs], \nɛfɹˈɪtɪk kɹˈa‍ɪsɪs], \n_ɛ_f_ɹ_ˈɪ_t_ɪ_k k_ɹ_ˈaɪ_s_ɪ_s]\

Definitions of NEPHRITIC CRISIS

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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