NEPHRITIS ANTIGEN (GP330)
\nɛfɹˈa͡ɪtɪs ˈantɪd͡ʒˌɛn d͡ʒˌiːpˈiː θɹˈiːhˈʌndɹədən θˈɜːti], \nɛfɹˈaɪtɪs ˈantɪdʒˌɛn dʒˌiːpˈiː θɹˈiːhˈʌndɹədən θˈɜːti], \n_ɛ_f_ɹ_ˈaɪ_t_ɪ_s ˈa_n_t_ɪ_dʒ_ˌɛ_n__ dʒ_ˌiː_p_ˈiː θ_ɹ_ˈiː_h_ˈʌ_n_d_ɹ_ə_d_ə_n θ_ˈɜː_t_i]\
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A LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in that it binds to a variety of ligands with relatively high affinity and may function in mediating the uptake and lysosomal degradation of macromolecules such as: LIPOPROTEINS, ENDOPEPTIDASES and PROTEASE INHIBITORS.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.