NUCLEOLYSIN
\njˈuːklɪˌɒlɪsˌɪn], \njˈuːklɪˌɒlɪsˌɪn], \n_j_ˈuː_k_l_ɪ__ˌɒ_l_ɪ_s_ˌɪ_n]\
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A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
By DataStellar Co., Ltd
