OUABAIN
\wˈɑːbe͡ɪn], \wˈɑːbeɪn], \w_ˈɑː_b_eɪ_n]\
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A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA (+)-K (+)-EXCHANGING ATPASE.
By DataStellar Co., Ltd
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A deadly glucosid, C30H46O2+7H2O, from an African arrow-poison: heart-stimulant and local anesthetic.
By Willam Alexander Newman Dorland
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A crystalline glucosid, C30H46O12+9H2O, or an amorphous form, obtained from ouabaio wood, and later from Strophanthus gratus. It has the same action as strophanthin, but appears more active when given by the vein or intramuscularly than strophanthin, though it seems to be absorbed somewhat slowly and uncertainly from the alimentary canal. It is also known as crystalline strophanthin, a term which has led to much confusion.
By Smith Ely Jelliffe
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.