RADICULOPATHY
\ɹˌadɪkjʊlˈɒpəθɪ], \ɹˌadɪkjʊlˈɒpəθɪ], \ɹ_ˌa_d_ɪ_k_j_ʊ_l_ˈɒ_p_ə_θ_ɪ]\
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Disease involving a spinal nerve root (see SPINAL NERVE ROOTS) which may result from compression related to INTERVERTEBRAL DISK DISPLACEMENT; SPINAL CORD INJURIES; SPINAL DISEASES; and other conditions. Clinical manifestations include radicular pain, weakness, and sensory loss referable to structures innervated by the involved nerve root.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.