SUPPURATIVE HIDRADENITIS
\sˈʌpjʊɹˌe͡ɪtɪv hˌɪdɹɐdənˈa͡ɪtɪs], \sˈʌpjʊɹˌeɪtɪv hˌɪdɹɐdənˈaɪtɪs], \s_ˈʌ_p_j_ʊ_ɹ_ˌeɪ_t_ɪ_v h_ˌɪ_d_ɹ_ɐ_d_ə_n_ˈaɪ_t_ɪ_s]\
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A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident. Hormonal mechanisms are expected in its pathogenesis.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.