AROMATASE
\ɐɹˈə͡ʊmɐtˌe͡ɪs], \ɐɹˈəʊmɐtˌeɪs], \ɐ_ɹ_ˈəʊ_m_ɐ_t_ˌeɪ_s]\
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An enzyme which converts androgens to estrogens by desaturating ring A of the steroid. This enzyme complex is located in the endoplasmic reticulum of estrogen-producing cells including ovaries, placenta, testicular Sertoli and Leydig cells, adipose, and brain tissues. The enzyme complex has two components, one of which is the CYP19 gene product, the aromatase cytochrome P-450. The other component is NADPH-cytochrome P-450 reductase which transfers reducing equivalents to P-450 (arom). EC 1.14.13.-.
By DataStellar Co., Ltd
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