GAMMA AMINOBUTYRIC ACID RECEPTORS
\ɡˈaməɹ ɐmˌɪnəbjuːtˈɪɹɪk ˈasɪd ɹɪsˈɛptəz], \ɡˈaməɹ ɐmˌɪnəbjuːtˈɪɹɪk ˈasɪd ɹɪsˈɛptəz], \ɡ_ˈa_m_ə_ɹ ɐ_m_ˌɪ_n_ə_b_j_uː_t_ˈɪ_ɹ_ɪ_k ˈa_s_ɪ_d ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
By DataStellar Co., Ltd
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