METACARPOPHALANGEAL

\mˌɛtəkˈɑːpəfˌalɐnd͡ʒˌi͡əl], \mˌɛtəkˈɑːpəfˌalɐnd‍ʒˌi‍əl], \m_ˌɛ_t_ə_k_ˈɑː_p_ə_f_ˌa_l_ɐ_n_dʒ_ˌiə_l]\
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1920 - A dictionary of scientific terms.
By Henderson, I. F.; Henderson, W. D.
 
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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