METACARPO-PHALANGIAN ARTICULATIONS
\mˌɛtəkˈɑːpə͡ʊfalˈaŋɡi͡ən ɑːtˌɪkjʊlˈe͡ɪʃənz], \mˌɛtəkˈɑːpəʊfalˈaŋɡiən ɑːtˌɪkjʊlˈeɪʃənz], \m_ˌɛ_t_ə_k_ˈɑː_p_əʊ_f_a_l_ˈa_ŋ_ɡ_iə_n ɑː_t_ˌɪ_k_j_ʊ_l_ˈeɪ_ʃ_ə_n_z]\
Definitions of METACARPO-PHALANGIAN ARTICULATIONS
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Are formed by the bones of the metacarpus and the corresponding phalanges. In these articulations, the bony surfaces are incrusted with cartilage, covered by a synovial membrane, and kept in connexion by means of an anterior and two lateral ligaments.
By Robley Dunglison
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.