PRO ACTH ENDORPHIN
\pɹˈə͡ʊ ˈakθ ɛndˈɔːfɪn], \pɹˈəʊ ˈakθ ɛndˈɔːfɪn], \p_ɹ_ˈəʊ ˈa_k_θ ɛ_n_d_ˈɔː_f_ɪ_n]\
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A precursor protein, MW 30,000, synthesized mainly in the anterior pituitary gland but also found in the hypothalamus, brain, and several peripheral tissues. It incorporates the amino acid sequences of ACTH and beta-lipotropin. These two hormones, in turn, contain the biologically active peptides MSH, corticotropin-like intermediate lobe peptide, alpha-lipotropin, endorphins, and methionine enkephalin.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.