SUBSTITUTION THERAPY
\sˌʌbstɪtjˈuːʃən θˈɛɹəpi], \sˌʌbstɪtjˈuːʃən θˈɛɹəpi], \s_ˌʌ_b_s_t_ɪ_t_j_ˈuː_ʃ_ə_n θ_ˈɛ_ɹ_ə_p_i]\
Definitions of SUBSTITUTION THERAPY
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.