TRYPSIN INHIBITOR, ALPHA 1 ANTITRYPSIN
\tɹˈɪpsɪn ɪnhˈɪbɪtə], \tɹˈɪpsɪn ɪnhˈɪbɪtə], \t_ɹ_ˈɪ_p_s_ɪ_n ɪ_n_h_ˈɪ_b_ɪ_t_ə]\
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Plasma glycoprotein member of the serpin superfamily which inhibits trypsin, neutrophil elastase, and other proteolytic enzymes. Commonly referred to as alpha 1-proteinase inhibitor (A1PI), it exists in over 30 different biochemical variant forms known collectively as the Pi (protease inhibitor) system. Hereditary A1PI deficiency is associated with pulmonary emphysema.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.