COAGULATION FACTOR I
\kə͡ʊˌaɡjʊlˈe͡ɪʃən fˈaktəɹ ˈa͡ɪ], \kəʊˌaɡjʊlˈeɪʃən fˈaktəɹ ˈaɪ], \k_əʊ_ˌa_ɡ_j_ʊ_l_ˈeɪ_ʃ_ə_n f_ˈa_k_t_ə_ɹ ˈaɪ]\
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Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
By DataStellar Co., Ltd
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