LECITHIN ACYLTRANSFERASE
\lˈɛsɪθˌɪn ɐkˈɪltɹɐnsfˌɜːɹe͡ɪz], \lˈɛsɪθˌɪn ɐkˈɪltɹɐnsfˌɜːɹeɪz], \l_ˈɛ_s_ɪ_θ_ˌɪ_n ɐ_k_ˈɪ_l_t_ɹ_ɐ_n_s_f_ˌɜː_ɹ_eɪ_z]\
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An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. EC 2.3.1.43.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.