VAN BOGAERT SCHERER EPSTEIN DISEASE
\vˈan bˈɒɡe͡ət ʃˈɜːɹəɹ ˈɛpsta͡ɪn dɪzˈiːz], \vˈan bˈɒɡeət ʃˈɜːɹəɹ ˈɛpstaɪn dɪzˈiːz], \v_ˈa_n b_ˈɒ_ɡ_eə_t ʃ_ˈɜː_ɹ_ə_ɹ ˈɛ_p_s_t_aɪ_n d_ɪ_z_ˈiː_z]\
Sort: Oldest first
-
A lipid storage disease, inherited as an autosomal recessive trait, characterized by xanthomas of the tendons, the white matter of the brain, and the lungs, and by spasticity, ataxia, pyramidal paresis, mental retardation, dementia, early cataracts, and atherosclerosis. It is associated with elevated plasma and tissue levels of cholestanol and defective bile synthesis, with the deposition of cholestanol in the central nervous system and myelin of peripheral nerves. The lesions contain cholesterol and dehydrocholesterol. (Dorland, 28th ed)
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- van allen
- van allen belt
- van beethoven
- van bogaert encephalitis
- van bogaert leukoencephalitis
- Van Bogaert Scherer Epstein Disease
- van bogaerts leukoencephalitis
- van buren
- van buren's disease
- van buren, john
- van buren, martin