ZINOSTATIN
\zˈɪnəstˌatɪn], \zˈɪnəstˌatɪn], \z_ˈɪ_n_ə_s_t_ˌa_t_ɪ_n]\
Sort: Oldest first
-
An antitumor isolate from the culture filtrate of the F-41 variant of Streptomyces carzinostaticus. It is a protein of known amino acid sequence with a molecular weight of approximately 11,500 and possessing a regulatory function on the metabolism of DNA. In this process, that is first an inhibition of DNA biosynthesis followed by the degradation of DNA, zinostatin functions in a manner analogous to that of the much higher molecular weight antibiotic MITOMYCIN. Zinostatin is also a potent cytostatic agent active against gram-positive organisms.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.